Structural Impact of Steroidal Glycoalkaloids: Barrier Integrity, Permeability, Metabolism, and Uptake in Intestinal Cells.

Lucas KeuterAlessa WolbeckMatthias KasimirLina SchürmannMatthias BehrensHans-Ulrich Humpf

Published in: Molecular nutrition & food research (2024)

Besides structure-activity relationships, this study provides new information on the overall effects of steroidal alkaloids on intestinal cells and closes a gap of knowledge for the metabolic pathway from oral uptake to final excretion.

Keyphrases

induced apoptosis
cell cycle arrest
healthcare
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endoplasmic reticulum stress
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oxidative stress
endothelial cells
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