The repeat FIT (RFIT) study: Does repeating faecal immunochemical tests provide reassurance and improve colorectal cancer detection?
Nicholas G FarkasLampros PalyvosJames W O'BrienKai Shing YuCarolyn PigottMartin Brunel WhyteIain JourdanTimothy RockallCallum G FraserSally C BentonPublished in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2024)
One or more negative FIT increases the sensitivity for CRC/SBD. Repeating FIT provides greater differentiation of patients with and without CRC/SBD compared to single FIT but is associated with decreased specificity and PPV. Multiple negative FIT may offer reassurance; however, application of repeating FIT may be restricted given the associated increase in investigations S1.
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