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Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells.

Anders W MatsonRob H HullsiekKate J DixonSam WangAnders J LindstedtRyan R FriessShee Kwan PhungTanya S FreedmanMartin FelicesEmily N TruckenbrodJianming WuJeffrey S MillerBruce Walcheck
Published in: bioRxiv : the preprint server for biology (2024)
Keyphrases
  • nk cells
  • induced apoptosis
  • signaling pathway
  • cell cycle arrest
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress