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Update on Thrombocytopenia in Pregnancy.

Simone Filipa Carrasqueira SubtilJorge Miguel Bastos MendesAna Luísa Fialho de Amaral AreiaJosé Paulo Achando Silva Moura
Published in: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia (2020)
Thrombocytopenia, defined as platelet count < 150,000 mm3, is frequently diagnosed by obstetricians since this parameter is included in routine surveillance during pregnancy, with an incidence of between 7 and 12%. Therefore, decisions regarding subsequent examination and management are primordial. While most of the cases are due to physiological changes, as gestational thrombocytopenia, other causes can be related to severe conditions that can lead to fetal or maternal death. Differentiating these conditions might be challenging: they can be pregnancy-specific (pre-eclampsia/HELLP syndrome [hemolysis, elevated liver enzymes, low platelets]), or not (immune thrombocytopenia purpura, thrombotic thrombocytopenic purpura or hemolytic uremic syndrome). Understanding the mechanisms and recognition of symptoms and signs is essential to decide an adequate line of investigation. The severity of thrombocytopenia, its etiology and gestational age dictates different treatment regimens.
Keyphrases
  • birth weight
  • gestational age
  • preterm birth
  • pregnancy outcomes
  • weight gain
  • pregnant women
  • public health
  • case report
  • risk factors
  • clinical practice
  • early onset
  • physical activity
  • germ cell