Alpha 1-adrenoceptor signalling contributes to toxic effects of catecholamine on electrical properties in cardiomyocytes.

Mengying HuangXuehui FanZhen YangLukas CyganekXin LiGoekhan YuecelHuan LanYingrui LiAngela WendelSiegfried LangKaren BiebackIbrahim El-Battrawy Xiao-Bo ZhouIbrahim AkinMartin Borggrefe

Published in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2021)

Alpha 1-adrenoceptor signalling plays important roles for arrhythmogenesis of TTS. Alpha-adrenoceptor blockers might be clinically helpful for treating arrhythmias in patients with TTS.

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