The Impact of Trimetazidine on Cardiac Fibrosis, Inflammation, and Function in Ischemic Cardiomyopathy Patients.

Noha M El-KhodaryAsser I GhoneimAhmed A El-TayaarEman M El-Touny

Published in: Cardiovascular drugs and therapy (2022)

Adjunctive TMZ therapy for ICM effectively improved vascular endothelial function and reduced inflammation. Furthermore, our exploratory findings may be used to provide new information on the potential effects of TMZ on myocardial fibrosis by downregulating CTGF.

Keyphrases

oxidative stress
end stage renal disease
left ventricular
ejection fraction
newly diagnosed
heart failure
peritoneal dialysis
risk assessment
patient reported outcomes
liver fibrosis
climate change