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Identification of novel inhibitors for TNFα, TNFR1 and TNFα-TNFR1 complex using pharmacophore-based approaches.

Madhu Sudhana SaddalaHu Huang
Published in: Journal of translational medicine (2019)
The new selective TNFα, TNFR1 and TNFα-TNFR1 complex inhibitors can serve as anti-inflammatory agents and are promising candidates for further research.
Keyphrases
  • rheumatoid arthritis
  • anti inflammatory
  • molecular docking
  • molecular dynamics simulations