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Amotosalen/UVA treatment inactivates T cells more effectively than the recommended gamma dose for prevention of transfusion-associated graft-versus-host disease.

Grace CastroPatricia A MerkelHannah E GiclasAndrew GibulaGillian E AndersenLaurence M CorashJin Sying LinJennifer GreenVijaya KnightAdonis Stassinopoulos
Published in: Transfusion (2018)
Amotosalen/UVA treatment more effectively inactivates T cells than the current standard of gamma irradiation (2500 cGy) for the prevention of TA-GVHD.
Keyphrases
  • cardiac surgery
  • acute kidney injury
  • combination therapy
  • acute myeloid leukemia
  • acute lymphoblastic leukemia
  • allogeneic hematopoietic stem cell transplantation