Aging aggravates acetaminophen-induced acute liver injury and inflammation through inordinate C/EBPα-BMP9 crosstalk.

Rui LiuWentao XuHe ZhuZijian DongHuke DongShi Yin

Published in: Cell & bioscience (2023)

In summary, the present study highlights the crucial roles played by C/EBPα-BMP9 crosstalk and provides insights into the interrelationship between hepatocytes and MΦs during acute liver injury.

Keyphrases

liver injury
drug induced
mesenchymal stem cells
oxidative stress
liver failure
bone regeneration
intensive care unit
respiratory failure
bone marrow
extracorporeal membrane oxygenation
acute respiratory distress syndrome
hepatitis b virus
aortic dissection