Low birth weight is a conditioning factor for podocyte alteration and steroid dependance in children with nephrotic syndrome.
Giovanni ContiDominique De VivoClaudia FedeStefania ArasiAngela AlibrandiRoberto ChimenzDomenico SantoroPublished in: Journal of nephrology (2018)
LBW children developing NS had higher risk of FSGS and CD, and needed heavier immunosuppressive therapy than those with NBW. These data might suggest a conditioning role for hemodynamic and podocyte changes due to reduced nephron mass in LBW.