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NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling.

Enchong ZhangZhengjie ChenWangmin LiuLin LinLina WuJohnny GuanJianfeng WangChuize KongJianbin BiMo Zhang
Published in: Journal of translational medicine (2024)
NCAPG2 is highly expressed in PCa, and its level is significantly associated with PCa prognosis. NCAPG2 promotes PCa malignancy and drives cancer stemness via the STAT3/c-MYC signaling axis, highlighting its potential as a therapeutic target for PCa.
Keyphrases
  • prostate cancer
  • stem cells
  • epithelial mesenchymal transition
  • cell proliferation
  • papillary thyroid
  • radical prostatectomy
  • cancer stem cells