Attenuation of psilocybin mushroom effects during and after SSRI/SNRI antidepressant use.

Natalie Gukasyan Roland R GriffithsDavid B YadenDenis G Antoine Sandeep M Nayak

Published in: Journal of psychopharmacology (Oxford, England) (2023)

SSRI/SNRIs appear to weaken psilocybin drug effects relative to a non-serotonergic antidepressant. This dampening effect may last as long as 3 months following antidepressant discontinuation.

Keyphrases

major depressive disorder
emergency department