Predicting Mortality in Sepsis: The Role of Dynamic Biomarker Changes and Clinical Scores-A Retrospective Cohort Study.

Norberth-Istvan VargaAdela-Teodora BeneaMadalina-Ianca SubaAdrian Vasile BotaCecilia Roberta AvramCasiana BoruTiberiu Liviu DragomirMirandolina PriscaTanasescu SoniaMonica SusanFlorin George Horhat

Published in: Diagnostics (Basel, Switzerland) (2024)

The dynamic changes in these inflammatory biomarkers, particularly PCT, CRP, and LAC, offer valuable prognostic information beyond their baseline levels in predicting 30-day mortality in severe infections. These findings highlight the importance of monitoring biomarker trends for early risk stratification and potential treatment guidance.

Keyphrases

cardiovascular events
risk factors
acute kidney injury
intensive care unit
oxidative stress
coronary artery disease
type diabetes
combination therapy
smoking cessation