Login / Signup

Oligoclonal IgG bands in chronic inflammatory polyradiculoneuropathies.

Marta RuizMarco PuthenparampilMarta CampagnoloFrancesca CastellaniAlessandro SalvalaggioSusanna RuggeroElisabetta ToffaninMario CacciavillaniPaolo GalloDiego FranciottaChiara Briani
Published in: Journal of neurology, neurosurgery, and psychiatry (2021)
Compared with NINP, CIDP, GBS and anti-MAG antibody neuropathies had a significantly increased CSF protein and blood-spinal nerve root barrier damage. Intrathecal humoral immune response is rare in our patients with CIDP. Systemic oligoclonal activation is more frequent, but not significantly different from what was detected in the control groups.
Keyphrases
  • immune response
  • oxidative stress
  • spinal cord
  • dendritic cells
  • toll like receptor
  • protein protein
  • drug induced
  • peripheral nerve
  • amino acid
  • binding protein
  • small molecule