Mutations in the Katnb1 gene cause left-right asymmetry and heart defects.

Milena B FurtadoD Jo MerrinerSilke BergerDanielle RhodesDuangporn JamsaiBrendan J Houston

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2017)

Katanin function is a critical regulator of heart development in mice. These findings are potentially relevant to human cardiac development. Developmental Dynamics 246:1027-1035, 2017. © 2017 Wiley Periodicals, Inc.

Keyphrases

heart failure
endothelial cells
atrial fibrillation
left ventricular
transcription factor
type diabetes
metabolic syndrome
skeletal muscle
insulin resistance