Early-life malnutrition role in memory, emotional behavior and motor impairments in early brain lesions with potential for neurodevelopmental disorders: a systematic review with meta-analysis.
Caio Matheus Santos da Silva CaladoRaul Manhães-de-CastroVanessa da Silva SouzaHenrique José Cavalcanti Bezerra GouveiaSabrina da Conceição PereiraMárcia Maria da SilvaGlayciele Leandro de AlbuquerqueBruno Monteiro Paiva LimaAugusto Vagner Soares Martins de LiraAna Elisa ToscanoPublished in: Nutritional neuroscience (2024)
Epigenetic modifications were noted in the hippocampus, hypothalamus, and prefrontal cortex depending on the type of dietetic exposure in early life. These findings demonstrate the impact of the double insult on regions involved in cognitive and behavioral processes. Additional studies are essential to understand the real impact of the double insults in the critical period.