Nontargeted Metabolomic Profiling of Huo-Tan-Chu-Shi Decoction in the Treatment of Coronary Heart Disease with Phlegm-damp Syndrome.

Zhaoying Liang Qiaohuang Zeng Xiaomin Ou Jing Cai Tao-Hua Lan Weihui Lu

Published in: Cardiology research and practice (2022)

HTCSD has a certain therapeutic effect in mice with CHD with phlegm-damp syndrome via reducing myocardial ischemia, hypertrophy, and fibrosis. The underlying mechanisms involve the regulation of phospholipid metabolism, necroptosis, and autophagy.

Keyphrases

case report
cell death
signaling pathway
oxidative stress
endoplasmic reticulum stress
heart failure
type diabetes
mass spectrometry
skeletal muscle
combination therapy