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In vitro chondrogenic potency of surplus chondrocytes from autologous transplantation procedures does not predict short-term clinical outcomes.

Ashraful IslamVegard FossumAnn Kristin HansenIlona UrbarovaGunnar KnutsenInigo Martinez-Zubiaurre
Published in: BMC musculoskeletal disorders (2019)
In our limited material, we found no correlation between in vitro cartilage-forming capacity and clinical outcomes, and argue on the limitations of using the chondrogenic potential of cells or markers for chondrogenesis as predictors of clinical outcomes.
Keyphrases
  • mesenchymal stem cells
  • induced apoptosis
  • cell therapy
  • bone marrow
  • extracellular matrix
  • stem cells
  • oxidative stress
  • climate change