Calycosin Alleviates Injury in Airway Epithelial Cells Caused by PM 2.5 Exposure via Activation of AMPK Signalling.

Chunyan WangJingjing LuoXiaoxue BaiShucheng HuaJing JieHan Liu Jinying Gao Lei Song

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

Calycosin effectively decreased the release of inflammatory cytokines and alleviated injury caused by PM 2.5. These effects were mediated through activation of AMPK to suppress NF-κB signalling.

Keyphrases

particulate matter
air pollution
skeletal muscle
heavy metals
polycyclic aromatic hydrocarbons
signaling pathway
protein kinase
lps induced
risk assessment
mouse model
immune response
cell proliferation
toll like receptor