Mesenchymal Stem Cell Transplantation Has a Regenerative Effect in Ischemic Myocardium: An Experimental Rat Model Evaluated by SPECT-CT Assessment.
Antonella KoutelaGeorge LoudosMaritina RouchotaDimitrios KletsasAndreas KaramerisGeorge VilarasGeorge C ZografosDespoina MyoteriDimitrios DougenisApostolos E PapaloisPublished in: Diagnostics (Basel, Switzerland) (2024)
The positive effect of mesenchymal stem cell transplantation in the ischemic myocardium was recorded. The application of SPECT-CT allowed a clear evaluation of both the quality and quantity of the living myocardium post-infarction, leading to a new approach in the research of cardiovascular diseases. From a clinical perspective, MSCT may be beneficial when accompanied by myocardial revascularization procedures.
Keyphrases
- mesenchymal stem cells
- cell therapy
- image quality
- dual energy
- umbilical cord
- computed tomography
- cardiovascular disease
- contrast enhanced
- bone marrow
- stem cells
- pet ct
- ischemia reperfusion injury
- positron emission tomography
- left ventricular
- percutaneous coronary intervention
- cerebral ischemia
- magnetic resonance imaging
- type diabetes
- magnetic resonance
- heart failure
- acute coronary syndrome
- coronary artery bypass grafting
- cardiovascular risk factors
- blood brain barrier
- oxidative stress
- coronary artery disease
- metabolic syndrome
- brain injury
- clinical evaluation