Physalin B inhibits cell proliferation and induces apoptosis in undifferentiated human gastric cancer HGC-27 cells.
Chunsheng FangCunte ChenYanjun YangKehan LiRili GaoDandan XuYouxue HuangZheng ChenZhuandi LiuShaohua ChenXibao YuYangqiu LiChengwu ZengPublished in: Asia-Pacific journal of clinical oncology (2021)
PB inhibits proliferation via cyclin-dependent kinase and induces caspase-dependent apoptosis in HGC-27 cells, suggesting that PB might be a novel and effective agent for undifferentiated GC therapy.
Keyphrases
- cell cycle arrest
- induced apoptosis
- cell death
- endoplasmic reticulum stress
- pi k akt
- cell proliferation
- oxidative stress
- heavy metals
- signaling pathway
- endothelial cells
- cell cycle
- stem cells
- high resolution
- mesenchymal stem cells
- induced pluripotent stem cells
- aqueous solution
- smoking cessation
- liquid chromatography