Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway.

Hui-Feng Zhu Yali ShaoLei QinJing-Huan WangShan FengYun-Bin JiangDong Wan

Published in: Drug design, development and therapy (2019)

Catalpol may contribute to neurogenesis in infarcted brain regions and help promote the survival of newborn neurons by activating BDNF, but not BDNF/TrkB signaling.

Keyphrases

stress induced
spinal cord
cerebral ischemia
oxidative stress
signaling pathway
endoplasmic reticulum stress
cell death
neural stem cells
cell cycle arrest
cell proliferation
brain injury
free survival