An ultra-high-performance liquid chromatography-tandem mass spectrometry method for the simultaneous quantitation of 10 alkaloids of Corydalis Decumbentis Rhizoma preparation in dog plasma and its application to a pharmacokinetic study.
Ying YuJiahui SunChunjuan YangHongrui DongZhenyue WangZhibin WangPublished in: Basic & clinical pharmacology & toxicology (2022)
of bicuculline, dehydrocorydaline, protopine, magnoflorine, tetrahydrojatrorrhizine, jatrorrhizine, berberine and coptisine were all significantly higher in enteric-coated capsules.
Keyphrases
- tandem mass spectrometry
- ultra high performance liquid chromatography
- high performance liquid chromatography
- liquid chromatography
- solid phase extraction
- gas chromatography
- simultaneous determination
- molecularly imprinted
- high resolution
- high resolution mass spectrometry
- mass spectrometry
- ms ms
- liquid chromatography tandem mass spectrometry