Short delay to initiate plasma exchange is the strongest predictor of outcome in severe attacks of NMO spectrum disorders.

Mickael BonnanRudy ValentinoStéphane DebeugnyHarold MerleJean-Louis FergéHossein MehdaouiPhilippe Cabre

Published in: Journal of neurology, neurosurgery, and psychiatry (2017)

These results confirm an improved clinical benefit of early initiation of PLEX during severe attacks of NMO-SD. Perceiving PLEX as a rescue therapy only after steroid failure could be deleterious.

Keyphrases

early onset
drug induced