Autologous chondrocyte grafting promotes bone formation in the posterolateral spine.

J Alex SielatyckiMasanori SaitoMasato YuasaStephanie N Moore-LotridgeSasidhar UppugantiJuan M ColazoAlexander A HysongJ Patton RobinetteAtsushi OkawaToshitaka YoshiiHerbert S SchwartzJeffry S Nyman Jonathan G Schoenecker

Published in: JOR spine (2018)

This proof-of-concept study indicates that hypertrophic chondrocytes can promote bone formation comparable to iliac crest bone graft. These findings provide the foundation for future studies to investigate the potential therapeutic use of hypertrophic chondrocytes in spinal fusion.

Keyphrases

extracellular matrix
spinal cord
bone mineral density
bone marrow
current status
cell therapy
case control
endovascular treatment
soft tissue
platelet rich plasma
bone loss
stem cells
postmenopausal women
mesenchymal stem cells