Methylation of serotonin regulating genes in cord blood cells: association with maternal metabolic parameters and correlation with methylation in peripheral blood cells during childhood and adolescence.

Ivona BečeheliMarina HorvatičekMaja PerićBarbara NikolićCyrielle HolukaMarija KlasićMarina IvaniševićMirta StarčevićGernot DesoyeDubravka HranilovićJonathan D TurnerJasminka Štefulj

Published in: Clinical epigenetics (2024)

Methylation of 5-HT regulating genes in cord blood cells is influenced by neonatal sex, with maternal metabolism playing an additional role. Inter-individual variations present in circulating blood cells at birth are still pronounced in childhood and adolescence.

Keyphrases

induced apoptosis
cord blood
cell cycle arrest
genome wide
peripheral blood
depressive symptoms
endoplasmic reticulum stress
signaling pathway
gene expression
cell death
cell proliferation
young adults
body mass index
physical activity
weight gain