Auto-inflammation and auto-immunity pathways are associated with emergence of BOS in pediatric lung transplantation.
Carol K ConradHaley HedlinHyunsook ChinDon HayesPeter S HeegerAlbert FaroSamuel B GoldfarbErnestina Melicoff-PortilloThalachallour MohanakumarJonah OdimMarc SchecterGregory A StorchGary A VisnerNikki M WilliamsKaren KeslerLara Danziger-IsakovStuart C SweetPublished in: Pediatric transplantation (2022)
Our results indicate that post-LTx survival in children may be linked to activation of alternate pathways of the immune system that affect airway remodeling in addition to activation of "classical" pathways that have been described in adult LTx recipients. These may indicate pathways to target for intervention.
Keyphrases