The mutation spectrum of Parkinson-disease-related genes in early-onset Parkinson's disease in ethnic Chinese.

Yong-Ping ChenShi-Hui YuGuo-Hui ZhangYan-Bing HouXiao-Jing GuRu-Wei OuYing ShenWei SongXue-Ping ChenBi ZhaoBei CaoLing-Yu ZhangMing-Ming SunFei-Fei LiuQian-Qian WeiKun-Cheng LiuJun-Yu LinTian-Mi YangJing YangYing WuZheng JiangJiao LiuYang-Fan ChengYi XiaoWei-Ming SuFei FengYing-Ying CaiShi-Rong LiTao HuXiao-Qin YuanQing-Qing ZhouNa ShaoSha MaHui Fang Shang

Published in: European journal of neurology (2022)

Our study reveals that the genetic spectrum of EOPD in Chinese, which may help develop genetic scanning strategies, provided more evidence supporting CHCHD2 in PD.

Keyphrases

early onset
parkinson disease
late onset
deep brain stimulation
genome wide
copy number
gene expression
electron microscopy