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Causes of red blood cell loss during extracorporeal membrane oxygenation.

Kyle S BilodeauNabiha Huq SaifeeWayne L Chandler
Published in: Transfusion (2023)
RLI (ml/L/h) is a more reliable quantitative indicator of RBC loss than transfusion rate (ml/kg) for pediatric patients on ECMO. Phlebotomy and intravascular hemolysis only account for 40% of RBC loss in non-bleeding ECMO patients. High REV generation suggests sublethal damage and extravascular clearance may be a cause of RBC loss on ECMO.
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