The protective role of postoperative radiation therapy in low and intermediate grade major salivary gland malignancies: A study of the Canadian Head and Neck Collaborative Research Initiative.
Gregoire B MorandAntoine EskanderRui FuJohn R De AlmeidaDavid GoldsteinHesameddin NorooziAli HosniHadi SeikalyPaul TabetJustin M PyneT Wayne MatthewsJoseph DortSteve NakoneshnyApostolos ChristopoulosHouda BahigStephanie Johnson-ObasekiNadia HuaMarc GaudetAlborz JooyaAnthony NicholsFrancisco LaxagueMatthew CecchiniJenny DuJustin ShapiroIrene KaramPeter T DziegielewskiKrishna HanubalBoban ErovicStefan GraslJoel DaviesEric MonteiroMaru GeteIan WitterickNader SadeghiKeith RichardsonGeorge ShenoudaAnastasios ManiakasVivianne LandryMichael GuptaKelvin ZhouAlex M MlynarekMarc PusztaszeriKhalil SultanemMichael P HierPublished in: Cancer (2023)
Postoperative radiation therapy may reduce LLR in some low and intermediate grade salivary gland cancers with adverse features, but it had no benefit in patients who had early stage, low-grade salivary gland cancer with negative margins.