NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid.

Hong-Guen LeeNa-Kyeong HongYoung Tae Chang

Published in: Chemical communications (Cambridge, England) (2023)

The fluorescent probe pair, NBD-B2 and Styryl-51F, selectively detects NMN over citric acid. NBD-B2 exhibits increased fluorescence, while Styryl-51F shows decreased fluorescence upon NMN addition. Their ratiometric fluorescence change enables highly sensitive and wide-range detection of NMN, effectively distinguishing it not only from citric acid but also other NAD boosters.

Keyphrases

fluorescent probe
living cells
single molecule
energy transfer
nitric oxide
sensitive detection
mass spectrometry
label free
loop mediated isothermal amplification
molecularly imprinted