Cardiometabolic Effects of DOCA-Salt in Mice Dependent on Ambient Temperature.
Connie C GrobeJohn J RehoDaeleon Brown-WilliamsAlisha A ZieglerNatalia M MathieuSamuel B R LawtonEva M FeketeDaniel T BrozoskiKelsey K WackmanColin M L BurnettPablo NakagawaCurt D SigmundJeffrey L SegarJustin L GrobePublished in: Hypertension (Dallas, Tex. : 1979) (2023)
Ambient temperature robustly influences behavioral and physiological functions in mice, including metabolic and cardiovascular phenotype development in response to DOCA-salt treatment. Studying cardiometabolic responses of mice at optimal ambient temperatures promises to improve the translational relevance of rodent models.