Honeysuckle-derived microRNA2911 inhibits tumor growth by targeting TGF-β1.

Chunyan LiuMengzhen XuLuocheng YanYulian WangZhen ZhouShaocong WangYajie SunJunfeng ZhangLei Dong

Published in: Chinese medicine (2021)

Taken together, honeysuckle-derived miR2911 showed an anti-tumor effect in colon cancer through targeting TGF-β1 mRNA. The down-regulation of TGF-β1 promoted T lymphocytes infiltration, and accordingly impeded the colon tumor development.

Keyphrases

transforming growth factor
cell proliferation
long non coding rna
cancer therapy
long noncoding rna
signaling pathway