Familial autoimmunity and risk of developing immune thrombocytopenia and Evans syndrome.
Michell M Lozano ChingaJames B BusselMark N FluchelJacob WilkesChong ZhangHuong D MeeksJessica A MeznarichPublished in: Pediatric blood & cancer (2024)
The findings suggest that familial autoimmunity may have a stronger association with the development of ITP rather than its duration. Twelve (57.1%) patients with ES reported autoimmunity in their relatives. UPDB analysis was omitted due to the small number of patients with ES. The use of population databases offers a unique opportunity to assess familial health and may provide clues about contributors to immune dysregulation features within families.