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Major disparities in patient-reported adherence compared to objective assessment of adherence using mass spectrometry: A prospective study in a tertiary-referral hypertension clinic.

James M G CurneenLouise RabbittDarragh BrowneDarragh F O'DonoghueYousef AlansariBrendan HarhenAilbhe Ní GhríofaJohn FergusonJohn William McEvoyDavid LappinDavid P FinnPaula M O'SheaMichael Conall Dennedy
Published in: British journal of clinical pharmacology (2022)
In patients attending a tertiary hypertension clinic, the combined use of spot urine mass spectrometry and self-reporting identifies higher rates of nonadherence when compared to either modality alone. Both techniques should be combined for more accurate detection of medication adherence.
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