Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies.
L T MøllehaveT SkaabyK S SimonsenB H ThuesenE L MortensenC H SandholtO PedersenNiels GrarupT HansenAllan LinnebergPublished in: European journal of clinical nutrition (2017)
Our results do not provide evidence for a causal effect of circulating folate or vitamin B12 on the risk of depression or anxiety. However, we cannot rule out small to moderate effects, and thus large scale studies are needed.