Heparin-binding protein in ventilator-induced lung injury.

Jonas TydénN LarssonS LehtipaloH HerwaldM HultinJ WalldénA F BehndigJ Johansson

Published in: Intensive care medicine experimental (2018)

In a model of VILI in pigs, levels of HBP in BALF increased over time compared to controls, while plasma levels did not differ between the two groups. HBP in BALF was high in intubated ICU patients in spite of the seemingly non-harmful ventilation, suggesting that inflammation from other causes might increase HBP levels.

Keyphrases

end stage renal disease
binding protein
mechanical ventilation
newly diagnosed
chronic kidney disease
intensive care unit
ejection fraction
oxidative stress
venous thromboembolism
prognostic factors
growth factor
patient reported outcomes
respiratory failure
drug induced