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A minimally invasive clinical model to test sunscreen toxicity based on oxidative stress levels using microbiopsy and confocal microscopy - a proof of concept study.

Miko YamadaLynlee L LinLydia Y T HangPaul J BeltH Peter SoyerAnthony P RaphaelTarl W Prow
Published in: International journal of cosmetic science (2020)
The data support the hypothesis that microbiopsy is a viable approach to study cosmeceutical- skin interactions in volunteers with capacity for molecular assays and high throughput with very low risk to the volunteer.
Keyphrases
  • high throughput
  • oxidative stress
  • minimally invasive
  • electronic health record
  • single cell
  • big data
  • induced apoptosis
  • soft tissue
  • ischemia reperfusion injury
  • machine learning
  • deep learning
  • artificial intelligence