[The efficacy of ethylmethylhydroxypyridine succinate in patients with cerebrovascular pathology complicated with diabetes mellitus and metabolic syndrome].
E V YekushevaE V BiryukovaPublished in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2021)
Arterial hypertension, diabetes mellitus, obesity and dyslipidemia continue to be the main risk factors for diseases of the circulatory system and the leading causes of mortality in the world, the combination of these diseases significantly increases the likelihood of the development and more rapid progression of cardiovascular and cerebrovascular pathology. Improving approaches to the diagnosis and treatment of these diseases is a priority problem in modern medicine. Currently, there is no universal drug that can influence all stages of pathological process in both cerebrovascular diseases and diabetes mellitus, and the problem of rational use of drugs in patients with comorbid pathology has not been completely resolved. A difficult clinical task includes not only the timely detection of the disease and the correct diagnosis, but also the choice of the safest and most effective medicine. A number of clinical studies have demonstrated the efficacy of mexidol in the treatment of this category of patients, which is determined by its complex, pleiotropic and multimodal mechanisms of action.
Keyphrases
- metabolic syndrome
- arterial hypertension
- end stage renal disease
- insulin resistance
- ejection fraction
- newly diagnosed
- type diabetes
- loop mediated isothermal amplification
- weight loss
- prognostic factors
- extracorporeal membrane oxygenation
- peritoneal dialysis
- coronary artery disease
- uric acid
- body mass index
- combination therapy
- patient reported outcomes
- patient reported
- cardiovascular risk factors