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Therapeutic index of lymphadenectomy among patients with pancreatic neuroendocrine tumors: A multi-institutional analysis.

Lu WuKota SaharaDiamantis I TsilimigrasShishir K MaithelGeorge A PoultsidesFlavio G RochaSharon M WeberRyan C FieldsKamran IdreesClifford S ChoFeng ShenTimothy M Pawliknull null
Published in: Journal of surgical oncology (2019)
LND was mostly beneficial among patients with pNETs >2 cm, Ki-67 ≥ 3%, and lesions located at the pancreatic head as identification of LNM was most common among individuals with these tumor characteristics. Evaluation of ≥8 LNs was associated with a higher likelihood of identifying LNM as well as a higher therapeutic index, and therefore this number of LNs should be considered the goal.
Keyphrases
  • neuroendocrine tumors
  • early stage
  • lymph node metastasis
  • sentinel lymph node
  • squamous cell carcinoma
  • neoadjuvant chemotherapy
  • radiation therapy
  • minimally invasive