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Sacubitril/valsartan cardioprotective effect against cisplatin-induced cardiotoxicity via modulation of VEGF/eNOS and TLR4/TNFα/IL6 signalling pathways.

Marwa Monier Mahmoud RefaieRehab Ahmed RifaaiAsmaa M A BayoumiSayed Shehata
Published in: The Journal of pharmacy and pharmacology (2023)
Sac/Val has an important cardioprotective effect against CIS cardiotoxicity with the involvement of eNOS.
Keyphrases
  • endothelial cells
  • toll like receptor
  • rheumatoid arthritis
  • immune response
  • nitric oxide synthase
  • inflammatory response
  • ejection fraction
  • vascular endothelial growth factor