MicroRNAs as the critical regulators of Cisplatin resistance in ovarian cancer cells.

Published in: Journal of ovarian research (2021)

It was observed that miRNAs mainly exert their role in cisplatin response through regulation of apoptosis, signaling pathways, and transcription factors in OC cells. This review highlighted the miRNAs as important regulators of cisplatin response in ovarian tumor cells. Moreover, present review paves the way of suggesting a non-invasive panel of prediction markers for cisplatin response among OC patients.

Keyphrases

transcription factor
cell cycle arrest
induced apoptosis
end stage renal disease
signaling pathway
endoplasmic reticulum stress
newly diagnosed
oxidative stress
cell death
pi k akt
peritoneal dialysis
epithelial mesenchymal transition
patient reported outcomes
dna binding