Targeting Myddosome Signaling in Waldenström's Macroglobulinemia with the Interleukin-1 Receptor-Associated Kinase 1/4 Inhibitor R191.

Haiwen NiFazal ShiraziVeerabhadran BaladandayuthapaniHeather LinIsere KuiatseHua WangRichard J JonesZuzana BerkovaYasumichi HitoshiStephen M AnsellSteven P TreonSheeba K ThomasHans C LeeZhiqiang WangR Eric DavisRobert Z Orlowski

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)

Taken together, these data support the translation of R191 as an approach to target IRAK1/4 to the clinic for patients with Waldenström's macroglobulinemia.

Keyphrases

electronic health record
primary care
cancer therapy
big data
deep learning