Utilization and outcomes of protamine after percutaneous left atrial appendage occlusion.

Alejandra Chavez PonceAhmed El ShaerSahar SamimiSamian SulaimanAlyssa HarrisMohamad Alkhouli
Published in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2023)
Protamine is used in approximately 50% of LAAO procedures and is associated with lower bleeding events and higher rates of same-day discharge. The higher vascular complication and tamponade is likely due to its ad-hoc use as a reversal agent in these patients.