Muscular MRI-based algorithm to differentiate inherited myopathies presenting with spinal rigidity.
Mickael TordjmanIvana DabajPascal LaforetAdrien FelterAna FerreiroMoustafa BiyoukarBruno Law-YeEdmar ZanoteliClaudia CastiglioniJohn RenduChristophe BeroudAlexandre ChamouniPascale RichardDominique MompointSusana Quijano-RoyRobert-Yves CarlierPublished in: European radiology (2018)
• Inherited myopathies are rare, diagnosis is challenging and genetic tests require specialized centres and often take years. • Inherited myopathies are often characterized by spinal rigidity. • Whole body magnetic resonance imaging is a unique tool to orientate the diagnosis of each inherited myopathy presenting with spinal rigidity. • Each inherited myopathy in this study has a specific pattern of affected muscles that orientate diagnosis. • A novel MRI-based algorithm, usable by every radiologist, can help the early diagnosis of these myopathies.