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Muscular MRI-based algorithm to differentiate inherited myopathies presenting with spinal rigidity.

Mickael TordjmanIvana DabajPascal LaforetAdrien FelterAna FerreiroMoustafa BiyoukarBruno Law-YeEdmar ZanoteliClaudia CastiglioniJohn RenduChristophe BeroudAlexandre ChamouniPascale RichardDominique MompointSusana Quijano-RoyRobert-Yves Carlier
Published in: European radiology (2018)
• Inherited myopathies are rare, diagnosis is challenging and genetic tests require specialized centres and often take years. • Inherited myopathies are often characterized by spinal rigidity. • Whole body magnetic resonance imaging is a unique tool to orientate the diagnosis of each inherited myopathy presenting with spinal rigidity. • Each inherited myopathy in this study has a specific pattern of affected muscles that orientate diagnosis. • A novel MRI-based algorithm, usable by every radiologist, can help the early diagnosis of these myopathies.
Keyphrases
  • magnetic resonance imaging
  • spinal cord
  • contrast enhanced
  • machine learning
  • deep learning
  • computed tomography
  • late onset
  • case report
  • magnetic resonance
  • gene expression
  • dna methylation
  • body composition