Brain MRIs may be of low value in most children diagnosed with isolated growth hormone deficiency.
Jessica A SchmittPaul ThorntonAvni N ShahA K M Falzur RahmanElizabeth KubotaPatrick RizzutoAnshu GuptaSena OrsdemirPaul B KaplowitzPublished in: Journal of pediatric endocrinology & metabolism : JPEM (2021)
Pathogenic MRIs were uncommon in patients diagnosed with GHD except in the group with peak GH<3 ng/mL. There was a high frequency of incidental findings which often resulted in referrals to neurosurgery and repeat MRIs. Given the high cost of brain MRIs, their routine use in patients diagnosed with isolated GHD, especially patients with peak GH of 7-10 ng/mL, should be reconsidered.