Interaction between G ALNT12 and C1GALT1 Associates with Galactose-Deficient IgA1 and IgA Nephropathy.

Yan-Na WangXu-Jie ZhouPei ChenGui-Zhen YuXue ZhangPing HouLi-Jun LiuSu-Fang ShiJi-Cheng LvHong Zhang

Published in: Journal of the American Society of Nephrology : JASN (2021)

Our data identify GALNT12 as a novel gene associated with galactose-deficient IgA1 and suggest novel genetic interactions. These findings support a key role of genetically conferred dysregulation of galactose-deficient IgA1 in the development of IgA nephropathy.

Keyphrases

genome wide
copy number
gene expression
artificial intelligence
data analysis