The First Successful Heart-Lung Transplant in a Korean Child with Humidifier Disinfectant-Associated Interstitial Lung Disease.
Won Kyoung JhangSeong Jong ParkEun LeeSong I YangSoo-Jong HongJu-Hee SeoHyung-Young KimJeong-Jun ParkTae Jin YunHyeong Ryul KimYong-Hee KimDong Kwan KimSeung-Il ParkSang Oh LeeSang-Bum HongTae Sun ShimIn Cheol ChoiJinho YuPublished in: Journal of Korean medical science (2016)
From 2006 to 2011, an outbreak of a particular type of childhood interstitial lung disease occurred in Korea. The condition was intractable and progressed to severe respiratory failure, with a high mortality rate. Moreover, in several familial cases, the disease affected young women and children simultaneously. Epidemiologic, animal, and post-interventional studies identified the cause as inhalation of humidifier disinfectants. Here, we report a 4-year-old girl who suffered from severe progressive respiratory failure. She could survive by 100 days of extracorporeal membrane oxygenation support and finally, underwent heart-lung transplantation. This is the first successful pediatric heart-lung transplantation carried out in Korea.
Keyphrases
- extracorporeal membrane oxygenation
- interstitial lung disease
- respiratory failure
- systemic sclerosis
- acute respiratory distress syndrome
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- heart failure
- early onset
- mechanical ventilation
- atrial fibrillation
- multiple sclerosis
- mental health
- young adults
- cardiovascular events
- type diabetes
- intensive care unit
- childhood cancer