Dickkopf-3 (DKK3) in Urine Identifies Patients with Short-Term Risk of eGFR Loss.

Stephen ZewingerThomas RauenMichael RudnickiGiuseppina FedericoMartina WagnerSarah TriemStefan J SchunkIoannis PetrakisDavid SchmitStefan WagenpfeilGunnar H HeineGert MayerJürgen FloegeDanilo FliserHermann-Josef GröneThimoteus Speer

Published in: Journal of the American Society of Nephrology : JASN (2018)

Urinary DKK3 levels identify patients at high risk for eGFR decline over the next 12 months regardless of the cause of kidney injury and beyond established biomarkers, potentially providing a tool to monitor CKD progression and assess effects of interventions.

Keyphrases

small cell lung cancer
end stage renal disease
chronic kidney disease
epidermal growth factor receptor
tyrosine kinase
ejection fraction
newly diagnosed
physical activity
peritoneal dialysis
prognostic factors
gene expression
patient reported outcomes
patient reported