Effect of high-dose vitamin C therapy on severe burn patients: a nationwide cohort study.

Mikio NakajimaMorita KojiroShotaro AsoHiroki MatsuiKiyohide FushimiYasuhiko KaitaHideaki GotoYoshihiro YamaguchiHideo Yasunaga

Published in: Critical care (London, England) (2019)

High-dose vitamin C therapy was associated with reduced mortality in patients with severe burns when used under a minimum threshold of 10 g within the first 2 days of admission. While "high-dose" vitamin C therapy lacks a universal definition, the present study reveals that different "high-dose" regimens may yield improved outcomes.

Keyphrases

high dose
stem cell transplantation
low dose
end stage renal disease
ejection fraction
early onset
chronic kidney disease
newly diagnosed
emergency department
type diabetes
stem cells
cardiovascular events
peritoneal dialysis
mesenchymal stem cells
insulin resistance
adipose tissue
patient reported outcomes